Mulberry Leaf Extract DNJ works through a combination of multiple pathways to maintain healthy blood sugar levels in the body
The research results over the years have shown that the hypoglycemic mechanism of DNJ is very complex, and it has multiple pharmacological and physiological effects. There are three DNJ hypoglycemic pathways that have been identified so far:
1.As an α-glucosidase inhibitor, it delays the absorption of sugar from food and reduces postprandial blood sugar;
2.As a glycogen phosphorylase inhibitor, it inhibits hepatic glycogenolysis and stabilizes fasting blood sugar
3.Has a certain effect of improving insulin resistance.
【Lower postprandial blood sugar】
Alpha-glucosidase is mainly distributed in the human small intestine and plays an important role in the decomposition of carbohydrates. They are responsible for breaking down oligosaccharides like disaccharides in food into monosaccharides like glucose. This glucose enters the body through the intestinal wall, causing a sharp rise in the bodys blood sugar concentration.
【Stable fasting blood sugar】
Liver glycogen can be decomposed into glucose under the action of glycogen phosphorylase, and released into the blood, which is supplied to muscles and other organs, and is an energy source for physical activities. With the mutual conversion of hepatic glycogen and glucose, normal blood glucose is in a dynamic balance.
【Improve insulin resistance】
Insulin resistance refers to a variety of reasons (mainly including genetic factors and obesity) that cause insulin to reduce the efficiency of glucose uptake and utilization, and the body compensates for excessive secretion of insulin. Thereby resulting in hyperinsulinemia, in order to maintain the stability of blood sugar in the body. If the human body is in a state of insulin resistance for a long time, it will greatly increase the burden on the pancreas, which may lead to the failure of the insulin secretion function of the pancreas, and then develop into diabetes.
DNJ can improve symptoms of insulin resistance by maintaining healthy blood sugar, correcting lipid metabolism, and increasing insulin sensitivity.
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