Swertiamarin is an iridoid compound isolated from Swertiapatens, a Gentianaceae plant. Bulk Swertiamarin 98% is white fine powder with bitter taste and slightly hygroscopic in the air. Soluble in methanol, ethanol, slightly soluble in water, insoluble in chloroform, petroleum ether. It is clinically applicable to pain caused by gastrointestinal spasm, gastroenteritis, intestinal ascariasis, biliary ascariasis, cholecystitis, cholelithiasis and other biliary tract diseases. Let’s learn about it together!
Swertiamarin Benefits
1. Effects on the liver
It was used in the treatment of acute liver injury in rats caused by D-galactosamine, and the results showed that it can protect the liver, detoxify, reduce enzymes, reduce hepatosplenomegaly, and enhance the phagocytic function of macrophages in the liver. In the live experiment on rats, it was found that it can reduce the damage of toxic substances to the liver, and also prevent the liver damage caused by hypoxia in rats. The picrosides in Swertia japonica have obvious inhibitory effect on liver cancer cells.
2. Antispasmodic effect
It can inhibit the autorhythmic activity of isolated ileum, uterus, gallbladder smooth muscle and bile duct sphincter in experimental animals, and can resist acetylcholine, histamine, norepinephrine, barium chloride, pituitary hormone Exciting effects on the above tissues and organs. Tests also show that it acts directly on intestinal smooth muscle and presents an antispasmodic effect.
3. Analgesic effect
Studies have shown that it can significantly inhibit the central nervous system, and has significant analgesic and sedative effects. The analgesic and antispasmodic effects are the pharmacological basis for its treatment of gastrointestinal pain.
Swertiamarin for Skin
Swertiamarin Extract has an inhibitory effect on β-D-glucuronidase. β-D-glucuronidase acts on the β-glucuronide to D-glucuronic acid, making its glucuronide bond add water The general term for decomposing enzymes, the greater the activity, the stronger the sweat odor, so it can be used in cosmetics to suppress body odor. In adipocyte culture, it has obvious proliferative effect on fibroblasts, indicating that it has the effect of revitalizing and repairing the skin, and can be used in anti-aging cosmetics. In the hair growth test of rats, it shows a good ability to promote hair growth, which is the effect of its active ingredients as drug glycosides, and can be used in hair growth products. In adipocyte cultures, it promotes lipolysis, suggesting that it can be used in slimming cosmetics.
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