Suanzaoren, Chinese medicine name. It is grown in hot, dry climates in northern China or anywhere, harvested in autumn when it is ripe and reddened, and the pulp of the fruit is removed to obtain the seed kernel, which is then crushed before decoction. It can be used unprocessed, heat is better for insomnia or dry fried at low temperature until the seeds turn brown. It has the effects of nourishing the heart and nourishing the liver, calming the heart and soothing the mind, abstaining from sweat, and promoting body fluids.
Nutritional Value
Pure Jujube Extract Jujuboside contains a lot of fatty oils and proteins, and contains alkaloids, sterols, triterpenes, jujube saponins, total flavonoids, total alkaloids, unsaturated fatty acids, vitamin C and potassium, sodium, calcium, zinc, iron , copper, manganese and other metal elements.
1. The total saponins, total flavonoids, total alkaloids and unsaturated fatty acids it contains have hypnotic and sedative effects.
2. The total saponins of jujube seed can obviously protect the myocardial injury caused by hypoxia and glucose and chlorpromazine, and can protect the myocardium.
3. Its alcohol infusion has a strong and lasting antihypertensive effect.
Pharmacological Action
①Sedative and hypnotic effects
Its decoction can show sedation and drowsiness when it is given to rats orally or intraperitoneally. No matter day or night, normal state or coffee, due to the excited state, Suanzaoren can show the above effects. , and show synergistic effect with barbiturates. It can be used continuously for 6 days, which can make animals sleep shallower and shorten the duration, that is, tolerance, but it can disappear after 1 week of drug withdrawal. Oral administration of it results in a significant reduction in the number of defensive motor conditioning, diffusion of internal inhibition, subsidence of conditioning, and suppression of morphine-induced mania in cats. There is no difference in the sedative effect of raw jujube kernels and fried jujube kernels, but the effect of raw jujube kernels is weak, and it will fail after long-term frying in oil. .
② Analgesic, anticonvulsant, cooling effect
③ Effects on the cardiovascular system
It can cause a persistent drop in blood pressure and heart block.
④ Effects on burns
When used alone or in combination with Schisandra chinensis, it can improve the survival rate of scalded mice, prolong the survival time, delay the occurrence and prolong the survival time of burn shock in rats, and reduce the edema of the burn area in the mice.
⑤ Other functions
It has an excitatory effect on the uterus, but has no inhibitory effect on the vomiting caused by aquamorphine in dogs. Does not antagonize caffeine intoxication in rabbits.
Book record effect
It is recorded very early in the classic of traditional Chinese medicine “Shen Nong‵s Materia Medica” that sour jujube can “enhance the five internal organs, lighten the body and prolong life”. Therefore, do not underestimate this wild fruit, it has great medicinal value, and can play the role of nourishing the liver, calming the heart, soothing the nerves, and reducing sweat. In medicine, it is commonly used to treat neurasthenia, upset insomnia, dreaminess, night sweats, irritability and other diseases. At the same time, it can achieve a certain nourishing and strengthening effect. The common traditional Chinese medicine “Sedation and Sleeping Pill” is made of it as the main ingredient.
Research efficacy now
(1) Modern research has shown that it is anti-arrhythmic, but it is ineffective for organic palpitations and palpitations. Such as rheumatic heart disease, there is a problem with the valve itself, and the tranquilizers are ineffective, which is a surgical problem. So sedatives are all functional.
(2) It also has certain nourishing properties, and has a weak nourishing effect on the yin blood of the heart and liver. Nourishes heart yin, heart blood, liver yin and liver blood, but it is not a tonic, and it cannot be an effect, but it is more suitable for deficiency syndromes.
(3) It is an important medicine for nourishing the mind and calming the nerves, and it has a good effect of calming the nerves. It is sweet and sour, astringent sweating, and is characteristic of heart yin deficiency or liver and kidney yin deficiency, frequent night sweats, upset and insomnia. It can be combined with other antiperspirants (Schisandra, Cornus) to treat excessive sweating. In ancient times, it was believed that it used cooked food for sleep, cooked and fried, and used raw food to wake up and sleep. This is a misunderstanding. Its pulp does this. Stir-frying should also be slightly fried, after which the soothing effect will be reduced. The powder works well. ;
Benefits
1) Anti-convulsive, analgesic, cooling
The water extract of this product can significantly reduce the convulsion rate and mortality caused by pentylenetetrazol. Intraperitoneal injection of Suanzaoren water decoction 5 g/kg can significantly reduce the lethality of strychnine in mice.
This product‵s water decoction 5g/kg mouse hot plate method has obvious analgesic effect. The intraperitoneal injection of 2.5 g/kg and 5 g/kg in rats and the oral administration of 40 g/kg in cats have the effect of lowering body temperature.
2) Cardiovascular
(1) Protect the myocardium: Jujube Extract Jujuboside for sale can obviously protect the myocardial damage caused by hypoxia, hypoglycemia and chlorpromazine. Intraperitoneal injection of its alcohol extract in rats can resist the electrocardiographic changes of experimental myocardial ischemia.
(2) Antiarrhythmic: its water extract has obvious antiarrhythmic effect.
(3) Antihypertensive: Sour jujube makes blood pressure easier to control, dilates capillaries, reduces blood viscosity, and improves microcirculation. It can soften and protect blood vessels, and has the effect of lowering blood lipids and cholesterol in the human body. It also has the effect of continuously lowering blood pressure.
(4) Lipid-lowering: It can significantly reduce serum total cholesterol (TC), triglyceride (TG), and low-density lipoprotein cholesterol (LDL-C) in normal rats and hyperlipidemia rats, and can increase high cholesterol. Density lipoprotein cholesterol (HDL_C), and alleviation of hepatic steatosis. It is rich in vitamin C, which can effectively lower cholesterol and prevent the occurrence of gallstones.
(5) Anti-atherosclerosis: Sour jujube seed oil can significantly reduce TC, TG and LDL in high-fat quails, and the incidence of cardiac valve and endocardial loosening and thickening can be significantly reduced in slices.
(6) Immunization
Its alcohol extract and jujube seed polysaccharide can significantly improve the phagocytic function of mouse mononuclear macrophages, promote lymphocyte transformation, enhance delayed-type hypersensitivity, promote the formation of hemolysin antibodies, and antagonize the effect of cyclophosphamide on delayed-type hypersensitivity reactions. Inhibition of allergic reactions; can also antagonize the immune damage caused by radiation. Helps to speed up human recovery, improve human immunity,
3) Antioxidant and anti-hypoxia
(1) Antioxidation: The water decoction of raw sour jujube seed can significantly increase the reduction of SOD in whole blood and liver tissue caused by endotoxin injection in mice. But the effect of fried jujube kernel is not obvious.
Bulk Jujube Extract Jujuboside can significantly reduce the content of MDA in rabbit liver homogenate and rabbit erythrocyte membrane, and significantly increase SOD, and its anti-lipid peroxidation effect is enhanced with the increase of drug concentration.
(2) Anti-hypoxia: This product can significantly improve the survival time of mice under decompression and hypoxia, and reduce the oxygen consumption of brain tissue. Suanzaoren water extract can significantly delay the death time of occlusion hypoxia in mice.
4) Other
(1) Anti-tumor: Suanzaoren oil can significantly prolong the survival time of mice with Ehrlich ascites cancer.
(2) Anti-burn: The alcohol extract of this product can improve the survival rate and survival time of hot water scald in mice. It also has obvious inhibitory effect on scalded edema, and it can be synergistic when used in combination with Schisandra chinensis.
(3) Suanzaoren has the effect of stimulating the uterus.
(4) Astringing sweat and producing body fluid: According to the Qing Dynasty medical classic “Benjing Fengyuan”, cooked sour jujube kernel can astringe semen, astringe sweat and produce body fluid; The stagnation of the gallbladder meridian. For sweating, night sweats embolism. (5) Nutritional value and therapeutic efficacy
It is rich in a lot of fatty oils, proteins, sterols, triterpenoids, jujube seed saponins and a variety of vitamins needed by the human body. Eating jujube seed has the functions of nourishing the liver, calming the heart, soothing the nerves, and astringing sweat.
We are Jujube Extract Jujuboside manufacturers, we guarantee our products are produced in strict according to standard and specification. We are constantly developing more products to meet market demand, if you have any requirements, please contact us freely. Email: info@lonierherb.com Whatsapp/Wechat: +86-18189137076
