Ashwagandha is an evergreen shrub that grows in parts of India, the Middle East and Africa. Its roots and fruits have been used medicinally for hundreds of years, so the plant is also known as “Indian ginseng”. It is a very beneficial plant in Indian medicine, not only in India but also in many western countries. It contains compounds of antioxidants and vitamins that help the body fight both internal stressors such as anxiety and external stressors such as infections.
So far, more than 12 alkaloids and more than 40 steroids have been isolated from Ashwagandha. Among them, ashwagandha (Withanolides) has attracted attention due to its wide range of pharmacological activities (anti-tumor, antibacterial, anti-inflammatory and immunomodulatory activities, etc.). Wholesale Ashwagandha Extract 5% Withanolides is a natural steroid compound with 28 carbon atoms and has the skeleton structure of ergostane. According to the different C-17 side chains, Withanolides can be divided into 2 types (Type A and Type B) (Fig. 2), most Withanolides belong to the Type A structure type. Studies have shown that there is a certain structure-activity relationship between the structure and activity of Withanolides, such as the α, β-unsaturated ketone structure of the A ring (left) and the 5β, 6β-epoxy group of the B ring (right) for its Essential group for antitumor activity.
1. Optimize sleep
Ashwagandha extract is a good helper against insomnia. Research from the University of Tsukuba in Japan shows that its extract contains triglycolic acid, which can promote people to enter the non-rapid eye movement sleep period and thus play a role in deepening sleep.
2. Improve memory
Relevant studies have shown that it can significantly improve the human body's instantaneous memory and general memory ability by supporting axons and dendrites and promoting cell regeneration in the brain and nervous system. Since Ashwagandha can degrade acetylcholinesterase activity, help improve concentration, and speed up the brain‵s processing of information, these have been proven in clinical trials.
3. Fight stress
While traditionally used by people in countries such as South Asia as a stress-fighting and energy-boosting tonic, researchers in the United States have found that it has excellent mood-sedating properties, soothes and calms the nervous system, and reduces oxidative damage from nervous tension.
4. Enhance thyroid function
It stimulates the thyroid to help it function. The maintenance of human energy requires a certain amount of thyroid hormone, which can help to maintain the balance of thyroid hormone levels.
5. Helps detoxify the body
It can help prevent certain diseases from appearing. It is thought to help protect against oxidation and detoxification, so it may protect the body from infection.
6. Stimulates the immune system
As an adaptogen, it may help reduce inflammation in the body and help the immune system work properly. It improves white blood cell counts and has been shown to help increase immune globulin production. Immunoglobulins are antibodies that fight diseases of the immune system and help the body make more of these antibodies naturally.
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