Huperzia Serrata is a rare and precious medicinal material, it is distributed all over the world. As usually, the whole herb is used as medicine, which has the functions of clearing away heat and detoxifying, promoting muscle and hemostasis, dissipating blood stasis and reducing swelling. Since 1980 Chinese pharmacists isolated Huperzine A from it, then attracted the attention of domestic and foreign experts. It has obvious improvement effects on enhancing memory, improving memory damage, improving the efficiency of mental activity, senile memory decline and Alzheimer‵s disease, adolescent learning disabilities and memory enhancement.
1. Why does it work?
As an acetylcholinesterase inhibitor, Huperzine A Powder can prevent the specific enzyme acetylcholinesterase from breaking down acetylcholine in the body, thereby improving memory and concentration. Acetylcholine is a neurotransmitter used in many processes in the body, which are chemical messages released by nerve cells to transmit signals to other cells in the body, such as neurons, gland cells, and muscle cells.
As we age, our brains undergo age-related neurodegenerative changes, oftern resulting in decreased cognition, memory and clarity, decreased concentration and mental agility, decreased nerve growth factors, and free radical damage to the brain Cell mitochondria, etc. Due to its inhibitory effect on acetylcholine in the body , Hup A can help to prevent these age-related cognitive declines.
2. What is main function ?
1) Anti-acetylcholinesterase effect
It has a highly selective inhibitory effect mainly through acetylcholinesterase, thereby reducing the hydrolysis of acetylcholine, and by activating N receptors or M receptors on the presynaptic membrane and antagonizing M receptors on the postsynaptic membrane, then enhance the function of acetylcholine, so as to enhance the learning and memory ability of AD patients and improve the cognitive and behavioral function.
At the same time, it also inhibits the G4 isoform of acetylcholinesterase, which is very common in mammalian brains. It also has greater or equal potency against other acetylcholinesterase inhibitors.
2) Antioxidant effect
After research, it was found that it can improve the survival rate of nerve cells and the activity of anti-peroxidase (such as glutathione peroxidase, superoxide dismutase, peroxidase), at the same time to reduce lipid peroxidation products such as malondialdehyde.
3) Protect nerve cells
It also has broad neuroprotective effects against organophosphate, glutamate and beta-amyloid neurotoxicity.
4) Anti-apoptotic effect
Studies have shown that it has a relieving effect on the apoptosis of hippocampal neurons in the brain, thereby improving learning and memory also.
3. Precautions for use
1) Pregnant women, lactating women, children do not use.
2) Patients with heart disease should use it with caution, because it may lower the heart rate, which may worsen related symptoms.
3) Patients with epilepsy should use it with caution, because it may affect neurotransmitters in the brain and may worsen related symptoms.
4) Patients with gastrointestinal obstruction, urinary tract or reproductive system obstruction, peptic ulcer, asthma or emphysema should use it with caution, because it increases tissue mucus and fluid secretion, which may worsen symptoms.
5) Do not use in combination with anticholinergic drugs, which may reduce the efficacy of the drug.
6) Do not use in combination with acetylcholinesterase inhibitors, which may increase the side effects of the drug.
7) Do not use in combination with cholinergic drugs, which may increase the side effects of the drug.
Huperzine A 1% Powder is a natural product with significant pharmacological effects in vitro and in vivo, and has great prospects for further development. After years of research and development, LonierHerb can currently provide Huperzia Serrata Extract Free Samples with different specifications, such as 1%, 5%, and 98%. You are welcome to write to us at any time! Email: info@lonierherb.com Whatsapp/Wechat: +86-13289383216
