Fucoidan is a water-soluble marine polysaccharide dietary fiber, rich in L-fucose (L-Fucose) and sulfate ester group (Sulfate ester group), is one of the unique physiologically active substances of brown algae. It was first discovered by Swedish scientist Kylin in brown algae (kelp, kelp, wakame, etc.). When the leaves and stems of seaweed are damaged by high waves or sea sand, the leaves of brown algae secrete a slimy substance—fucoidan. Prevent bacterial invasion; when seaweed is exposed to the air due to low tide, fucoidan has strong water retention properties, which can keep seaweed moist, prevent leaves from drying out and die, and prolong the life of seaweed. Modern medical research has found that it has various health effects such as eliminating Helicobacter pylori, repairing gastric mucosa, improving kidney function, anti-tumor and improving immunity. Let’s learn about it together!
Mechanism
It has been hailed as a natural anticancer agent, and its antitumor activity has been increasingly reported. Fucoidan improves immunity and inhibits cancer cells mainly through the following three mechanisms:
1) Initiate the apoptosis mechanism of cancer cells, terminate their infinite proliferation state, and induce apoptosis of cancer cells;
2) Enhance human immunity and greatly enhance the ability to remove abnormal cells.
3) Inhibit the angiogenesis of cancer cells, so that they cannot get the nutrients needed for growth and undergo apoptosis.
Its outstanding physiological activity has attracted the attention of countries all over the world. The fast-paced lifestyle in modern society makes more and more people in the “sub-healthy” state. It has rich physiological activities and can effectively improve human health. At present, fucoidan has entered the market in Japan and the United States as a drug for the prevention and treatment of cancer and thrombosis.
Benefit
1) Regulate immunity
Inject it into B-cell lymphoma mice respectively to observe the activation of the immune system and the growth of B-cell lymphoma cells in the mice. Fucoidan extracted from wakame spore leaves can effectively activate the immune system in mice, enhance the ability of immune cells to kill tumors, and inhibit the growth of tumor cells.
2) Nourishing and protecting the stomach
Wholesale Fucoidan Extract Powder has an anti-ulcer effect, helps to prevent the adhesion of Helicobacter pylori on the gastric mucosa, and reduces the possibility of capsule formation.
3) Hypoglycemic effect
Experts from Ocean University of China have done experiments to prove that it has the function of lowering blood fat. Atherosclerosis is the main pathological basis of many cardiovascular and cerebrovascular diseases, and high blood lipid and high lipid peroxide content are important factors leading to atherosclerosis. Therefore, reducing blood lipids and high lipid peroxide levels is an important measure to prevent the occurrence of atherosclerosis. It helps to reduce blood fat in human body. Therefore, it can play a certain role in weight loss for certain obese groups.
4) Anticoagulant effect
It has an anticoagulant effect and can significantly prolong the activated partial thromboplastin time, indicating that it has an obvious anticoagulant effect.
It has obvious anticoagulant and fibrinolytic pharmacological activities, and its activity is enhanced with the increase of fucoidan concentration, but because the relative molecular weight of polysaccharides is large and difficult to be absorbed, the anticoagulant effect is not as good as heparin, only It is suitable for patients with high blood viscosity and can only be used as a drug or health product to prevent thrombosis. Studies have found that the anticoagulant effect of polysaccharides is also related to the way of intake, and the effect of intravenous injection is significantly higher than that of intraperitoneal injection.
5) Regulate kidney health
The well-known Haikun Shenxi Capsules, which are used to treat damp turbidity syndrome caused by chronic renal failure, are mainly composed of fucoidan, which shows its efficacy in regulating kidney health.
Notable effects in cosmetics
Researchers from the School of Chemistry and Materials Engineering, Jiangnan University found that fucoidan can be used as an excellent natural moisturizer in skin care products.
The researchers first tested the hygroscopicity and moisture retention. Under the conditions of 81% and 43% humidity and a room temperature of 20°C, the hygroscopicity and moisture retention of fucoidan were tested respectively, and it was mixed with glycerin, butanediol and alginic acid. Commonly used raw materials such as sodium are compared.
The study selected 20 qualified volunteers to test the inner arms of the subjects. The subjects entered the test room half an hour in advance (temperature 20°C, relative humidity 50%±2%), exposed hands and forearms, and entered the test state. Delineate multiple small areas of 3cm*3cm on the same arm, with an interval of more than 1cm, apply different samples evenly to the test area with a finger cot, and measure the skin moisture content of each area with a skin moisture tester.
A series of research results showed that:
1)Hygroscopicity: at 45% humidity, within the first eight hours, sodium alginate∠butanediol∠glycerin∠CEFSF. And at 81% relative humidity, within the first eight hours,sodium alginate∠Glycerol∠butanediol∠fucoidan.after eight hors, the hygroscopicity of CEFSF slowed down, which may be related to the structure of its polyhydroxy macromolecules;
2)Moisturizing performance: at 81% relative humidity, alginic acid∠butanediol∠glycerol∠fucoidan. It shows that it has good moisturizing properties and can replace common humectants.
3)Inhibit skin water loss: 3% and 5% fucoidan are better than glycerin in inhibiting water loss. A series of studies have shown that it can be used as an excellent moisturizer in skin care cosmetics.
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