What is epigallocatechin gallate?
EGCG, Epigallocatechin Gallate is the most effective active ingredient in catechins, accounting for about 8% to 13% of the gross weight of green tea, and is also the component with the highest content in catechins. EGCG is an ester formed by α-bisphenol benzopyran and gallic acid, which has the general antioxidant properties of phenols. There are 6 ortho-phenolic hydroxyl groups in its molecular structure, so it has many properties superior to other catechins.
What are the health benefits of epigallocatechin gallate?
1. Antioxidant effect
EGCG Green Tea Extract has a potent antioxidant activity that is at least 100 times more than that of vitamin C and 25 times greater than that of vitamin E. It can prevent oxidative stress in cells, neutralize free radicals, and shield cells from harm-all of which are linked to heart disease, cancer, and other serious illnesses.
2. Anti-inflammatory effect
Because of its anti-inflammatory qualities, EGCG can decrease the release of inflammatory mediators and suppress inflammatory reactions and enzyme activities linked to inflammation.
3. Auxiliary anti-cancer effect
Some studies have shown that EGCG has an inhibitory effect on a variety of cancers, including breast cancer, lung cancer, and colon cancer. It can inhibit tumor growth and spread by regulating the cell cycle, promoting cell apoptosis, and inhibiting tumor angiogenesis.
4. Promote cardiovascular health
It helps lower cholesterol levels, inhibit platelet aggregation and thrombosis, thereby maintaining cardiovascular health.
5. Regulate weight
EGCG may have a certain effect on weight management and metabolic regulation. It can promote fat oxidation and heat energy consumption, and fight obesity and metabolic syndrome.
6. Antibacterial and antiviral effects
EGCG also has antibacterial and antiviral properties, which can interfere with the growth and reproduction of microorganisms.
7. Deodorant and anti-caries effects
EGCG can be used as a deodorant and anti-caries agent in the food industry and daily chemical products.
EGCG Green Tea Extract application?
Chinese green tea contains a substance called EGCG. It makes up 9%-13% of the gross weight of green tea and is the primary water-soluble and active component. It also has the highest amount of any catechin. The antioxidant activity of EGCG is at least 100 times that of vitamin C and 25 times that of vitamin E due to its unique stereochemical structure. It can shield DNA and cells from harm, which is thought to be connected to heart disease, cancer, and other serious illnesses. The capacity of EGCG to scavenge (antioxidant) oxygen free radicals is responsible for these benefits.
In the fight against cancer and heart disease, EGCG is crucial. Furthermore, it is employed as a tumor multidrug resistance reversal agent, which can lessen cardiac toxicity and increase cancer cells' sensitivity to chemotherapy.
In terms of green tea catechins and polyphenols, EGCG is the primary constituent. Catechins include EGCG, EGC, ECG, EC, GCG, and so on. Of these, EC has the highest antioxidant action. According to numerous studies, EGCG can prevent DNA damage from free radicals, withstand radiation and UV rays, prevent lipid peroxidation, lower serum levels of low-density, ultra-low-density, and triglycerides, interfere with the signaling necessary for cancer cell survival, inhibit carcinogens in the diet, work with other enzymes and antioxidants in the intestines, liver, and lungs to block the activity of certain carcinogens, scavenge free radicals, fend off the effects of pollution, sun exposure, and smoking, and prevent and treat skin.
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