Dipotassium Glycyrrhizate Powder (DPG for short) is an active ingredient extracted from the root of the legume licorice (Glycyrrhizauralensis Fisch.). Dipotassium glycyrrhizate is not only suitable for hair and skin care, but also for oral hygiene care.
1. Skin Care:
Whitening - Inhibits melanin production and brightens skin tone. Anti-inflammatory - suitable for the treatment of skin inflammations such as wounds, eczema, burns, etc., and care for sensitive, fragile and irritable skin.
Glycyrrhizate can inhibit the production of melanin. In the experimental study, the back skin of guinea pigs was selected. Under UVB irradiation, the skin pretreated with 0.5%potassium glycyrrhizinate had a higher whiteness coefficient (L value) than the skin of the control group. Significantly, the experimental results show that dipotassium glycyrrhizate has a significant inhibitory effect on melanin production, which can be used to prevent skin pigmentation and melanin production after sun exposure, and is a potential skin whitening agent.
2. Oral and Scalp Care:
For the treatment of gum inflammation, oral hygiene and dental care, relieve itchy scalp.Dipotassium glycyrrhizate acts on hormone receptors on cell membranes, affects ion channels, activates or inhibits enzyme activity, regulates substance metabolism and cholinergic nerve excitability, thereby reducing the permeability of capillary walls and cell membranes , achieve the purpose of reducing inflammatory exudation, and inhibit the formation and release of histamine and other toxic substances, so as to play a good anti-inflammatory effect.
When dipotassium glycyrrhizate acts on LPS-stimulated RAW264.7 cells, it can inhibit the secretion of inflammatory mediator NO and inflammatory cytokine IL-6 to varying degrees.
Therefore, dipotassium glycyrrhizate in cosmetics can help reduce skin redness and irritation that are common in various diseases such as rosacea and psoriasis. Another clinical trial has shown that dipotassium glycyrrhizate can effectively treat atopic dermatitis.
Additive dosage: 0.1-1.0%
Applicable dosage forms: facial cleanser, toner, essence, lotion, cream, gel, eye cream, etc.
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