NANA Sialic Acid

NANA Sialic Acid, CAS 131-48-6, Molecular Formula: C11H19NO9 , is an acidic amino sugar with 9 carbon atoms and a pyranose structure, and also is one of the eight essential glyconutrients for the human body. It was originally isolated from submandibular gland mucin, hence the name. Sialic acid usually exists in the form of oligosaccharides, glycolipids or glycoproteins. In the human body, the content in the brain is the highest, which is 15 times that of internal organs such as liver and lungs. The main food sources of Acetylneuraminic Acid are bird‵s nest and breast milk, and it is also found in milk, eggs and cheese.

NANA N- Acetylneuraminic Acid is white fine powder, soluble in water and methanol, slightly soluble in ethanol, insoluble in ether, acetone and chloroform. There are more than 50 known sialic acids, the most common of which are Neu5Ac (N-acetylneuraminic acid) and Neu5Gc (N-glycolylneuraminic acid). This ingredient is widely used in nutraceutical, food, cosmetic, and research applications. Produced under strict quality control standards, it ensures high purity, consistency, and reliable performance for diverse industrial needs..

The safety of N-acetylneuraminic acid has undergone rigorous assessment by authoritative organizations across numerous countries. When derived from legitimate sources and utilized at reasonable dosages, it is widely recognized as safe for all population groups. Globally, mainstream food safety regulatory authorities have incorporated it into the scope of legal food additives or nutritional supplements, further validating its compliance with stringent safety protocols.

1) The National Health and Family Planning Commission of China included it in the catalog of new food raw materials in 2017,

2) US FDA approved Bulk NANA Sialic Acid for infant milk powder and general food in 2016

3) European Food Safety Authority (EFSA) Decree No. 259/97 in 2017 has approved it as a new food raw material.

Brief Manufacturing Process:

Immobilized enzyme catalyzes the synthesis of N-Acetylneuraminic acid from sodium pyruvate and N-Acetylglucosamine, followed by decolorization with activated carbon, vacuum concentration, addition of acetic acid for crystallization, and filtration to obtain crude crystals. The crude crystals are recrystallized (dissolved in water and crystallized with acetic acid), pulped with ethanol, dried, and tested for quality before packaging.

Q1: Do you have factory ?
Yes, we have a 1500m2 factory with modern equipment, welcome to visit our factory. When you have the details schedule, please kindly let me know in advance.

Q2: What makes your product stand out?
A: Our NANA features excellent solubility, high purity, and carefully controlled production processes, ensuring optimal performance across a wide range of applications.

Q3: What does the product look like?
A: It is a white fine powder with good solubility in water and methanol, slightly soluble in ethanol, and insoluble in ether, acetone, and chloroform.

Q4: What are the typical applications?
A: It is food grade, and widely used as a raw material in nutraceuticals, functional foods, cosmetics, and scientific research.

Q5: How do you ensure product quality?
A: We follow strict quality control procedures throughout production, including raw material selection, manufacturing, and testing, to ensure high purity, consistency, and batch stability.

Q6: Do you provide technical support or customization?
A: Yes, we offer flexible specifications, customization services, and professional technical support to meet different customer requirements.

Q7: What is your delivery time ?
As usual, our delivery time is about 1~3 days after receipt of payments, please kindly confirm with your sales manager in advance.

Q8: How can I start working with you?
A: Simply contact us with your requirements on the botton or send email, and our team will respond promptly with product details, quotations, and tailored solutions.

- All goods are manufactured in GMP standard facilities.

- All goods are released after inspection by our independent laboratory or third party.

- All goods are transported by professional freight companies.

- Allergen Free

- Gluten Free

- GMO Free

- Non-Irradiation

Independent laboratory guarantee each batch are high quality and qualified, of course, we can arrange Sialic Acid Powder Samples to third party, such as Eurofins, SGS, or your designated laboratory before shipment.

1) Improve intelligence and memory

It is an important building block of gangliosides in the brain. The content of sialic acid in the nerve cell membrane is 20 times that of other cells. Because the transmission of brain information and the conduction of nerve impulses must be realized through synapses, and it is a brain nutrient that acts on brain cell membranes and synapses, so it can promote memory and intellectual development.

2) Anti-recognition

Between molecules and cells, between cells and cells, and between cells and the outside world, the Acetylneuraminic Acid at the end of the sugar chain can serve as a recognition site or mask the recognition site. It can effectively prevent some important antigenic sites and recognition marks on the cell surface, thereby protecting these saccharides from being recognized and degraded by the surrounding immune system.

3) Antibacterial, antiviral, antitumor

Due to the special structure of the 9-carbon amino sugar of Neu5Ac Sialic Acid , there is no enzyme to degrade the substance in the digestive tract system. Therefore, the polypeptide conjugate formed by it will not be degraded by the enzymes in the digestive tract. When it enter the intestine, the specific sialic acid-polypeptide conjugates can form competitive binding with pathogenic bacteria, toxins, and virions entering the intestinal tract, thereby preventing intestinal toxins, pathogenic bacteria, and virions from binding to intestinal mucosal cells. It can be seen that adding sialic acid to food can improve the antibacterial, detoxification and antiviral capabilities of the intestine.

4) Improve human immunity

NANA N- Acetylneuraminic Acid will not be degraded by digestive enzymes in the digestive system, and can enter the intestinal tract to prevent pathogenic microorganisms from adsorbing on intestinal cells, and play a role in resisting various pathogenic bacteria, then improve human immunity.

5) Improve absorption of vitamins and minerals

Sialic acid carries an extremely strong negative charge, which can make red blood cells and other cells repel each other, avoiding meaningless cell interactions in the blood circulation. According to the principle that the opposite sex attracts each other, the positively charged minerals and some vitamins that enter the intestinal tract are easily combined with sialic acid with a strong negative charge . Therefore, it can improve the absorption capacity of the intestinal tract for minerals and vitamins, thereby enhancing the body‵s absorption of nutrients.

1) Pre-shipment Samples is available for your confirmation before the bulk goods shipments.

2) As a NANA Sialic Acid factory in China, we ensure Manufacturing Date is not older than 2 months at the time of order.

3) As per your quantity, we will choose the best mode of transportation, by sea , by air or International courier company.

4) Each batch of our products are analyzed before shipments, and guaranteed to comply with Specification.

LonierHerb with strict product quality, professional sales team, We are committed to promoting the development of natural health all the time.NANA Sialic Acid are one of our main products,we have enough stock ,if you are interested,welcome to contact by e-mail: info@lonierherb.com or Whatsapp/Wechat:86-13289383216.

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