Shaanxi LonierHerb Bio-Technology Co., Ltd is one of the most professional manufacturers and suppliers of s-adenosyl-l-methionine (same) in China, featured by quality products and good price. Please rest assured to wholesale bulk natural s-adenosyl-l-methionine (same) for sale here from our factory. Contact us for free sample.
Product Introduction
S-Adenosyl-L-Methionine (SAMe) is a naturally occurring compound found in the body, involved in various biochemical processes such as methylation and cellular function. It is synthesized in the liver from methionine and adenosine triphosphate (ATP) and is widely recognized in scientific research. SAMe is also known by several names, including S-adenosylmethionine, SAM-e, and AdoMet, and is used globally in different product formats across nutraceutical and research fields.
LonierHerb SAMe (Ademetionine Disulfate Tosylate) is manufactured using advanced biological enzymatic conversion technology, followed by purification through freeze-drying to ensure high purity and stability. The entire production process is automated and conducted under strict quality control systems, complying with internationally recognized standards such as EP and USP. This product is widely used as a raw material in dietary supplements and related formulations, with common dosage forms including lyophilized powder, tablets, and capsules.
As a professional SAMe supplier, we offer consistent quality, reliable supply capacity, and flexible solutions to meet diverse customer
requirements. Our SAMe powder is a semi-finished raw material intended for qualified manufacturers, traders, and research institutions. It is not recommended for direct personal use. We welcome your inquiries and look forward to supporting your business with high-quality ingredients and professional service.

Brief Information
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Product Name |
S-Adenosyl-L-methionine Disulfate Tosylate |
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Main Specification |
95.0%~103% |
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Appearance |
White to off-white Powder |
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pH |
1.0 ~2.0 |
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CAS |
97540-22-2 |
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Chemical Formula |
C22H34N6O16S4 |
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Molecular Weight |
766.78 |
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EC Number |
249-946-8 |
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Structural Formula |
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LonierHerb Supports
★ Sample Support: 10g samples for your pre-testing needs
★ Service Support: 24/7 dedicated professional assistance
★ Shipment Support: In-stock availability with delivery within 2 to 3 working days upon order confirmation
★ Freight Support: Access to premium logistics options including FedEx, TNT, DHL, UPS and top-tier freight forwarders
★ Document Support: Comprehensive technical and compliance documentation, covering Technical Data Sheets (TDS), Certificates of Analysis (COA), Allergen Lists, MSDS, Nutrition Information, Certificates of Origin and more
Technical Data Sheet
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Product Name |
S-Adenosyl-L-methionine Disulfate Tosylate |
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CAS |
97540-22-2 |
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Test Items |
Test Standard |
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Appearance |
White to off-white Powder |
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S-Adenosyl-L-methionine Disulfate Tosylate |
95.0 % ~103.0% |
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Identification |
Infrared: Conforms to the Reference Spectrum |
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HPLC: The retention time of the major peak corresponds to the reference sample |
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S, S-Isomer (HPLC) |
≥ 75.0% |
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SAM-e ION (HPLC) |
49.5% ~ 54.7% |
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P-Toluenesulfonic Acid |
21.0% ~ 24.0% |
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Content of Sulfate (SO4) (HPLC) |
23.5% ~ 26.5% |
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Loss on Drying |
≤3.0% |
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Sulphated Ash |
≤0.5% |
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pH |
1.0 ~2.0 |
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Related substances(HPLC): |
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S-adenosyl-L-homocysteine |
∠1.0% |
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Adenine |
∠1.0% |
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Methylthioadenosine |
∠1.5% |
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Adenosine |
∠1.0% |
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Total Impurities |
∠3.5% |
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Heavy Metal |
≤10 ppm |
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Total Aerobic Count |
≤1000cfu/g |
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Yeast and Moulds |
≤100cfu/g |
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E-Coli |
Negative |
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Salmonella |
Negative |
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Staphylococcus Aureus |
Negative |
Safety and Side Effects
● Information on the long-term safety of S-Adenosyl-L-Methionine (SAMe) is limited because participants in most studies only took it for a short time. However, in a study of alcohol-related liver disease, participants took it for 2 years, and no serious side effects were reported.
● If you are pregnant or nursing a child, if you take medication or other dietary supplements, if you have bipolar disorder or Parkinson‵s disease, if you are HIV positive, do not use S-Adenosylmethionine, or consult your doctor, please use under doctor‵s order.
● At present, its side effects are uncommon, and when they do occur, they are usually mild problems, such as nausea or indigestion.

Test Reports from Third Laboratory
We have cooperated with other famous third-party laboratories, such as Eurofins, SGS , we can arrange S-Adenosyl-L-Methionine (SAMe) Free Samples to reinspect according to customer's requirements before shipments. Of course, even to the laboratory designated by the customers.

Package and Delivery Time

What are the benefits of S-Adenosyl-L-Methionine?
1) Promotes positive mood balance
SAMe Adenosyl Methionine could enhance the brain‵s dopamine and serotonin neurotransmitters metabolism and function of information transfer.
2) Joint Health
Raw SAME tosylate disulfate in alleviating pain and improve joint function.
3)A dietary supplement
S Adenosyl Methionine Powder can improves mood, maintains the liver and soothes joints in the US market.
4) Antioxidant
It has good antioxidant activity, can remove free radicals in the body, and delay the aging of cells and tissues.
5) Liver detoxification
It has the effect of promoting liver detoxification, which can help the liver reduce toxins in the body and protect liver function.
6) Protect the nervous system
Bulk SAME tosylate disulfate can protect the normal function of the nervous system and help relieve neuropathic pain, neuritis and other diseases.
7) Regulating immunity
It also has an immunoregulatory effect, which can regulate the function of the immune system and enhance human immunity.
Why choose LonierHerb Factory?
1) More than 10 years of production experience of Adenosylmethionine and first class modern production equipment to confirm that each batch of goods you received is qualified and complied
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2) With the concept of "Quality First, Integrity First", Shaanxi LonierHerb Bio-Technology Co., Ltd. are strictly performing the standard in production and quality control.
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3) With sufficient inventory, safe and package for long distance transportation, we are ready to arrange shipment for you at any time.
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4) Well-know Shipping Agent will ship the cargs to you safe and fast.
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If you want to buy S-Adenosyl-L-Methionine (SAMe), or need the further information, such SAMe S Adenosyl L Methionine price, COA, Samples , please contact and enquiry to us immediately, your satisfaction is our first priority. THANK YOU ! Email: info@lonierherb.com Whatsapp/Wechat: +86-13289383216
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