Shaanxi LonierHerb Bio-Technology Co., Ltd is one of the most professional manufacturers and suppliers of camptothecin cpt in China, featured by quality products and good price. Please rest assured to wholesale bulk natural camptothecin cpt for sale here from our factory. Contact us for free sample.
Products Description
Camptothecin CPT is a valuable natural alkaloid derived from the bark and stem of the camptothecin tree. Research on this compound shows that it has powerful anti-inflammatory and antioxidant properties that help protect cells in the body from damage. CPT has received a lot of attention from the scientific community in recent years due to the growing interest in CPT as a potentially beneficial health ingredient. Studies have shown that it has several health benefits, including the ability to fight oxidative stress and inflammation. Ongoing research on this compound promises to uncover more potential health benefits in the future.
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Product Name |
CPT |
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CAS |
7689-03-4 |
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Appearance |
Light yellow crystal powder |
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Purity |
98.0% |
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Test Method |
HPLC |
Technical Data Sheet
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Product Information |
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Product Name |
Camptothecin |
|
CAS |
7689-03-4 |
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Test Items |
Test Standard |
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Assay(HPLC) |
≥98.0% |
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Appearance |
Slightly yellowish orystal powder |
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Identification |
A.HPLC |
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B.IR |
|
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Loss of drying |
∠1.0% |
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Ash content |
∠0.3% |
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Related substances |
Single Impurity≤1.0.% |
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Total Impurities≤2.0.% |
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CPT Benefits
1) Cancer raw materials
It works by blocking the action of an enzyme called topoisomerase I, which is essential for DNA replication and cell division. By inhibiting this enzyme, camptothecin prevents cancer cells from dividing and growing, thereby slowing the progression of the disease. Studies have shown that it can induce apoptosis (programmed cell death) in cancer cells, killing them without affecting normal cells. It has also been found to be effective in combination with other cancer treatments such as chemotherapy and radiation, further enhancing its efficacy.
2) Antiviral properties
It has also been shown to have antiviral properties, making it a potential treatment for viral infections. It has been found to be effective against a variety of viruses. It works by inhibiting the activity of viral DNA polymerase, which is critical for viral replication. In addition to its antiviral activity, it has also been found to have immunomodulatory effects, helping to strengthen the immune system and improve overall health.
3) Neuroprotective properties
It has neuroprotective properties, which means it protects the brain and nervous system from damage. This has important implications for the treatment of neurodegenerative diseases. In animal studies, CPT was found to increase levels of neuroprotective proteins in the brain, improving cognitive function and reducing the risk of nerve damage.
4) Anti-inflammatory properties
It has also been found to have anti-inflammatory properties, making it useful as an ingredient in the treatment of inflammatory conditions such as rheumatoid arthritis, Crohn's disease, and ulcerative colitis. It works by inhibiting the production of inflammatory cytokines, which are responsible for inflammatory symptoms.
Mechanism of camptothecin
1) Its function is related to its mechanism of action as a DNA topoisomerase I inhibitor. DNA topoisomerase is an important enzyme responsible for regulating the topological state of DNA and maintaining DNA by relieving the torsional stress accumulated during the parallel transcription of various complex binary structures of DNA. Camptothecin specifically targets DNA topoisomerase I, an enzyme necessary for the relaxation of DNA supercoiling by creating single-strand breaks in DNA. DNA and topoisomerase I, which cause DNA damage and trigger cell death.
2) The mechanism of its inhibition of DNA topoisomerase I is complex and involves multiple steps. First, camptothecin binds to the blocking form of the enzyme, trapping it in a state that prevents DNA from passing through the enzyme's active site. This results in high levels of cleavage complexes between the enzyme and the DNA, resulting in double-strand DNA breaks. Second, the resulting double-strand DNA breaks alter several cellular processes, including DNA repair mechanisms, the cell cycle, and finally the induction of apoptosis, which is triggered by the accumulation of DNA damage, leading to cancer cell death.
How can you get Samples?
1) If we have samples stock, we can supply some free samples for your testing.
2) If there is no samples stock, you should pay samples cost, then we will prepare for you specially.
3) When you confirm the formal order, we will reduce your samples cost from your invoice directly.
4) For our old and reputable clients, we supply samples on free all the time.
Product Packing
LonierHerb is committed to customer service and development, we can pack according to customer's requirements, for example, 100g/aluminum foil bag, 1kg/aluminum foil bag or 100g/bottle.
Test Reports from Third Laboratory
We have cooperated with other famous third-party laboratories, such as Eurofins, SGS , we can arrange the Samples to reinspect according to customer’s requirements before shipments. Of course, even to the laboratory designated by the customers.
Contact Us
For the further information of Camptothecin CPT, please contact and enquiry LonierHerb factory directly, Free Samples, COA, MSDS, Allergen List and so on will be sent to you at the first time. Your satisfaction is our first priority. THANK YOU !
Email: info@lonierherb.com Whatsapp/Wechat: +86-18189137076
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